GASTROENTEROLOGY ARTICLE OF THE WEEK

JUNE 10, 1999

Becker AE, Grinspoon SK, Klibanski A, Herzog DB. Eating Disorders. N Engl J Med 1999;340;1092-1098
  1. Pharmacologic therapy of anorexia nervosa:
    1. when used alone is often successful
    2. may help sustain recovery in patients who have regained most of their weight
    3. antidepressants should be routinely used as these patients are at risk for suicide
    4. is of limited efficacy in patients with inadequate nutritional status.
  1. Features on physical examination that are suggestive or typical of an eating disorder include
    1. tachycardia and hypotension due to volume depletion
    2. swelling of parotid glands
    3. abrasions of the dorsum of the hands
    4. gingival hypertrophy
    5. abdominal distention secondary to intestinal dilation
    6. severe electrolyte disturbances

 

True or False

    3. Patients with anorexia nervosa are frequently substance abusers

    4. Binge eaters are frequently over-concerned about body weight or shape

    5. TPN should be initiated soon after admission in patients with eating disorders

    6. Approximately 85% of people with anorexia nervosa recover fully with therapy

    7. The main difference between binge eating disorder and bulimia nervosa is the absence of purging in the            former.

    8. Delayed gastric emptying is frequently present in eating disorders and should not be interpreted as the            cause of the eating disorder

    9. Estrogen replacement in amenorrheic patients with eating disorders is an important strategy to prevent           or reverse osteoporosis

    10. Bulimia is more likely than anorexia nervosa to respond to pharmacologic therapy, fluoxetine (Prozac)              is the drug of choice

    11. EKG abnormalities indicate the presence of severe electrolyte imbalance.

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