GASTROENTEROLOGY ARTICLE OF THE WEEK
April 22, 2004
Talley NJ. Dyspepsia. Gastroenterology 2003;125:1219-26.
1. Peptic ulcer disease accounts for what percent of dyspepsia symptoms:
a. 50%
b. 5%
c. 10%
d. 75%
2. Symptoms that are typical or consistent with a diagnosis of dyspepsia include
a. RLQ pain
b. bloating, fullness
c. weight loss
d. diarrhea
e. chest pain
3. H. pylori eradication and dyspepsia
a. In most cases, reflux symptoms become worse after eradication (F) only in those
with severe body gastritis
b. Successful H. pylori therapy will not abolish dyspepsia symptoms in about 1/3 of
infected patients
c. The majority of dyspepsia patients improve after H. pylori eradication
d. Maybe about 1 in 15 dyspepsia patients treated for H. pylori will improve
True or False
4. Patients with dyspepsia who present with symptoms that are highly suggestive for reflux, almost always have GERD when studied.
5. One third of “cured” H. pylori ulcer patients develop non-ulcer dyspepsia
6. Patients with predominantly early satiety symptoms may respond to medications that relax the fundus such as buspirone or tegaserod.
7. Low dose TCA’s may play a role in patients with dyspepsia, no response to PPI’s and normal endoscopy.
8. Intermittent dysphagia is an important alarm symptom that usually reveals organic disease when evaluated
9. PPI’s are clearly superior to H2RA in the treatment of univestigated “true” non-ulcer dyspepsia.
10. Gastric emptying studies are usually helpful in the management of patients with dyspepsia