GASTROENTEROLOGY ARTICLE OF THE WEEK
April 21, 2011
Bohm ME, Richter JE. Review article: Esophageal dilation in adults with eosinophilic esophagitis. Aliment Pharmacol Ther 2011;33:748-757.
1. The main pathophysiologic mechanisms of dysphagia in EoE is
a. eosinophilic-mediated inflammation without fibrosis
b. mucosal remodeling due to the chronic inflammatory process
c. deep ulcerations healing with fibrotic tissue
d. subepithelial fibrosis
2. To allow for an unrestricted diet with minimal to no dysphagia, the final dilation diameter should be
a. 13mm
b. 15mm
c. 16mm
d. 18mm
True or False
3. Dilation in cases of EoE usually results in deep mucosal tears, perforation are rare, but long-term improvement is extremely rare.
4. TTS balloons are preferred for dilating EoE, as they cause less pain and are more effective
5. Improvement in dysphagia after dilation is usually accompanied by a decrease in eosinophils in esophageal biopsies.
6. Chest pain, often persisting several days, is common after dilation for EoE
7. After dilation for EoE with Savary dilators, the endoscope should be reinserted to assess for the number and depth of esophageal tears.