GASTROENTEROLOGY ARTICLE OF THE WEEK
August 20, 2009
Cover TL, Blaser MJ. Helicobacter pylori in health and disease. Gastroenterology 2009;136:1863-1873.
1. Persons with CagA+ strains of H. pylori are more likely to have which of the following:
a. Erosive GERD
b. Duodenal ulcers
c. Barrett’s esophagus
d. Gastric adenocarcinoma
e. Asthma and atopic diseases
True or False
2. Histologic gastritis is present in 100% of subjects colonized with H. pylori
3. H. pylori colonization is associated with a reduced production of ghrelin by the stomach, which corrects to normal after eradication.
4. Even Travis Rutland has virtually every mucosal and cutaneous surface colonized by microbes
5. Strains of H. pylori that produce CagA, VacA and/or BabA are more likely to cause increased gatric epithelial cell injury
6. Humans are the only natural host for H. pylori.
7. Atrophic gastritis caused by H. pylori is characterized by abundant H. pylori organisms on biopsy.
8. CagA positive strains are more resistant to eradication.