GASTROENTEROLOGY ARTICLE OF THE WEEK
September 8, 2011
Kumar A, Auron M, Aneja A, et al. Inflammatory bowel disease: perioperative and pharmacological considerations. Mayo Clin Proc 2011;86:748-757.
1. Main excretory pathway for ASA compounds is:
a. stool
b. P450 cytochrome system
c. bile
d. kidneys
e. pancreas
2. Which of the following drugs is associated with increased risk of perioperative infections?
a. corticosteroids
b. ASA compounds
c. purine analogues
d. cyclosporine
e. methotrexate
f. Infliximab
True or False
3. Routine low dose heparin prophylaxis for venous thrombosis may be insufficient for IBD patients undergoing major abdominal surgery
4. Adrenally suppressed patients who undergo major surgery need to stay on stress-dose steroids for the entire post-operative period or up to 10 days.
5. A patient who underwent total colectomy and ileo-anal pull through for UC may resume ASA 3-5 days after surgery
6. A patient on less than 5mg a day of prednisone is not likely to be adrenally suppressed.
7. Thrombosis prophylaxis could prevent blindness in postoperative patients with IBD