GASTROENTEROLOGY ARTICLE OF THE WEEK

February 9, 2012 

Lin J, Koo JH, Abi-Hanna D.  Management of patients following detection of unsuspected lesions by PET imaging.  Clin Gastroenterol Hepatol 2011;9:1025-1032. 

1.  Focal incidental uptake of FDG by the colon during PET scan has a positive predictive value for finding a colon lesion on colonoscopy of:

            a.  80 – 85%

            b.  20 – 30%

            c.  50 – 80%

            d.  >90% 

True or False  

2. FDG PET is not a sensitive test to detect colon cancer  

3.  Focal uptake of FDG in the colon is less common and often associated with colonic pathology.  

4.  Physiologic pattern of segmental colon uptake of FDG is most common in the cecum  

5.  Segmental colonic uptake of FDG during PET CT maybe secondary to oral contrast administration  

6.  Diffuse uptake of FDG by the colon is common and may be increased in patients with diarrhea or constipation  

7.  Metformin may cause prominent diffuse bowel uptake of FDG, which may mimic active colitis.  

8.  A patient with no colonic symptoms who is noted to have diffuse colonic uptake on PET CT can be safely observed without a colonoscopy.   

9.  Patients with multifocal FDG uptake in the colon who have no colon symptoms can be safely observed without a colonoscopy.  

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