GASTROENTEROLOGY ARTICLE OF THE WEEK

August 9, 2007

 

AGA. American Gastroenterological Association Institute Medical Position Statement on the use of gastrointestinal medications in pregnancy.   Gastroenterology 2006;131:278-282 

1.  Which of the following medications should never be used during pregnancy

            a. ribavirin

            b. ranitidine

            c. castor oil

            d. tetracycline

            e. infliximab

            f.  doxycycline

            g. sodium bicarbonate

            h. tetracycline

            i.  peptobismol

True or False

2.  When doing endoscopy in a pregnant patient, propofol is the sedative of choice

3.  Benzodiazepines can be used freely and are preferred for endoscopic sedation

4.  Patients with Wilson’s disease should continue penicillamine at full dose  throughout pregnancy, otherwise liver failure will occur

5.  Tacrolimus therapy in liver transplant patients must be continued during pregnancy and is associated with an increased risk of malformations

6.  If a benzodiazepine is to be used for sedation, diazepam is safer than midazolam

7.  Polyethylene lavage is low risk, and should be used instead of phosphate preps

8.  Metoclopramide should not be used for nausea during pregnancy

9.  Kaopectate should be the first line drug for the treatment of diarrhea during pregnancy

10.  Hepatitis A vaccine is a live virus vaccine and should not be administered during pregnancy

11.  Non-selective beta blockers should be avoided during pregnancy

12.  TCA’s and SSRI’s when used in IBS, should be discontinued during pregnancy

13.  The drug of choice for diarrhea in pregnancy is Rifaximin or trimethoprim-sulfametoxazole

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