
GASTROENTEROLOGY ARTICLE OF THE WEEK
February 9, 2006
Blair JE, Kusne S. Bacterial, mycobacterial and Protozoal infections after liver transplantation – Part I. Liv Transpl 2005;11:1452-59.
1. Factors that enhance the patient susceptibility to opportunistic infections include
a. patient’s age
b. acute organ rejection
c. re-transplantation
d. antiobiotic regimen
e. chronic hepatitis B, C or HIV infection
2. Tuberculosis after transplant
a. usually becomes clinically evident in the first 3 months
b. is usually secondary to reactivation of a dormant infection
c. cavitary tuberculosis is the most common presentation
d. Fever, weight loss and night sweats are the usual presenting complaints
e. Disseminated infections are common, often involving the GI tract
True or False
3. Opportunistic infections classically develop during the first 3 weeks after transplant
4. The majority of bacterial infections occur within 2 months of the liver transplant.
5. Pneumonia caused by pportunistic organisms is more common in the first 4 weeks post transplant
6. Hepatic artery thrombosis may present as cholangitis or hepatic abscess after transplantation.
7. Aspergillus pneumonia is most common in the first month post transplant.
8. Toxoplasmosis is more common after liver transplants compared to heart transplants.